The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Jul. 19, 2018
Applicant:
Rush University Medical Center, Chicago, IL (US);
Inventors:
Assignee:
RUSH UNIVERSITY MEDICAL CENTER, Chicago, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 37/06 (2006.01); A61K 31/52 (2006.01); C12N 15/113 (2010.01); C12Q 1/6883 (2018.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/52 (2013.01); A61P 37/06 (2018.01); C12N 15/1137 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/172 (2013.01); G01N 33/5091 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present invention generally relates to methods of determining susceptibility of a subject to developing an inflammatory disorder and to methods of treating the disorder based on the subject's susceptibility. In one embodiment, the method includes determining expression levels of full-length MTHFR encoding mRNA and shortened MTHFR encoding mRNA initiated at intron 3 in a cell from the subject.