The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Jun. 09, 2023
Applicants:

Relay Therapeutics, Inc., Cambridge, MA (US);

D.e. Shaw Research, Llc, New York, NY (US);

Inventors:

Lucian V. Dipietro, Cambridge, MA (US);

Kelley C. Shortsleeves, Cambridge, MA (US);

Thomas H. Mclean, Cambridge, MA (US);

Alexandre Larivee, Montreal, CA;

Fabrizio Giordanetto, New York, NY (US);

André Lescarbeau, Cambridge, MA (US);

Alessandro Boezio, Cambridge, MA (US);

Hanmo Zhang, Cambridge, MA (US);

Assignees:

Relay Therapeutics, Inc., Cambridge, MA (US);

D. E. Shaw Research, LLC, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4035 (2006.01); A61B 5/00 (2006.01); C07D 209/46 (2006.01); C07D 487/04 (2006.01); H04R 25/00 (2006.01);
U.S. Cl.
CPC ...
H04R 25/554 (2013.01); A61B 5/0026 (2013.01); A61B 5/746 (2013.01); C07D 487/04 (2013.01); H04R 2225/55 (2013.01);
Abstract

The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of PI3K-α enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with PI3K-α signaling with the compounds and compositions of the disclosure.


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