The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Jan. 03, 2022
Korea Advanced Institute of Science and Technology, Daejeon, KR;
JaeByum Chang, Daejeon, KR;
Junyoung Seo, Daejeon, KR;
Young-Gyu Yoon, Daejeon, KR;
Hyunwoo Kim, Daejeon, KR;
Jee Won Kim, Daejeon, KR;
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, Daejeon, KR;
Abstract
Methods and apparatuses for multicolor unmixing may involve iterative mutual information minimization in a simultaneous channel update structure. A plurality of images may be obtained with respect to a plurality of fluorophores labeled on different biomolecules, respectively. Images of the fluorophores may be unmixed from the obtained images, respectively, while simultaneously minimizing mutual information shared between the obtained images based on all permutation combinations of the obtained images. Signals having three or more fluorophores whose emission spectra are overlapped in one spectral range can be more accurately unmixed.