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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12216736 B1

PDFFull Text
Date of Patent:
Feb. 04, 2025

Filed:

Nov. 08, 2021

Reducing probability of glass breakage in drug delivery devices

Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Sean Fitzgibbon, Camarillo, CA (US);

Christopher R. Folk, San Diego, CA (US);

Julian Jazayeri, Woodland Hills, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:

MARSHALL, GERSTEIN & BORUN LLP

Primary Examiner:

Iftekhar A Khan

Int. Cl.
CPC ...
G06F 17/18 (2006.01); A61M 5/20 (2006.01); A61M 5/315 (2006.01); A61M 5/32 (2006.01); G06F 17/13 (2006.01); G06F 30/17 (2020.01); G06F 30/20 (2020.01); G06F 111/08 (2020.01); G06F 111/10 (2020.01); G06F 113/08 (2020.01); G16H 20/17 (2018.01);
U.S. Cl.
CPC ...
G06F 17/18 (2013.01); A61M 5/2033 (2013.01); A61M 5/315 (2013.01); G06F 30/17 (2020.01); G06F 30/20 (2020.01); G16H 20/17 (2018.01); A61M 2005/206 (2013.01); A61M 5/3202 (2013.01); A61M 2205/3327 (2013.01); A61M 2205/3331 (2013.01); A61M 2205/3375 (2013.01); A61M 2205/50 (2013.01); A61M 2205/70 (2013.01); A61M 2207/00 (2013.01); G06F 17/13 (2013.01); G06F 2111/08 (2020.01); G06F 2111/10 (2020.01); G06F 2113/08 (2020.01);
Abstract

A method for determining predicted failure rates of drug injection devices includes receiving a set of parameters specifying physical properties of a syringe, a liquid drug, and a drug injection device configured to deliver the liquid drug to a patient via the syringe, the drug injection device including a mechanism that drives a plunger rod toward a plunger of the syringe encased in a syringe carrier. The method also includes receiving failure rate data specifying a measured rate of failure of the drug injection device in response to various peak pressures within the syringe, applying the set of parameters to a kinematic model of the drug injection device to determine a predicted peak pressure within the syringe, determining a probability of failure of the drug injection device using the failure rate data and predicted peak pressure, and providing an indication of the determined probability of failure to an output device.

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