The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Nov. 07, 2019
Applicant:

Ajou University Industry-academic Cooperation Foundation, Suwon-si, KR;

Inventors:

Yong Sung Kim, Suwon-si, KR;

Hae-Sim Park, Seoul, KR;

Jung Eun Kim, Seoul, KR;

Keunok Jung, Suwon-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61P 29/00 (2006.01); C07K 16/28 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6869 (2013.01); A61K 47/6845 (2017.08); A61P 29/00 (2018.01); C07K 16/2866 (2013.01); G01N 33/6893 (2013.01); G01N 2333/7155 (2013.01); G01N 2800/24 (2013.01);
Abstract

An antibody or antigen-binding fragment thereof, which binds with a high pM-level affinity to a human IL-4 receptor alpha chain that is a human IL-4 receptor, is provided. The antibody or antigen-binding fragment has a different epitope and a different antigen dissociation rate than existing antibodies. A nucleic acid encoding the antibody or antigen-binding fragment thereof, a vector including the nucleic acid, a cell transformed with the vector, a method for producing the antibody or antigen-binding fragment thereof, a conjugate comprising the antibody or antigen-binding fragment thereof, a composition for preventing or treating inflammatory diseases, and a composition for diagnosing inflammatory diseases are disclosed.


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