The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
May. 20, 2020
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
Heather Dawn Agnew, Culver City, CA (US);
Bert Tsunyin Lai, Culver City, CA (US);
Anders Eliasen, Culver City, CA (US);
Assignee:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); C07K 1/06 (2006.01); C07K 5/08 (2006.01); C07K 5/10 (2006.01); C07K 7/06 (2006.01); C12N 9/02 (2006.01); G01N 33/68 (2006.01); G01N 33/534 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); C07K 5/10 (2013.01); C07K 7/06 (2013.01); C12N 9/0069 (2013.01); G01N 33/68 (2013.01); C07K 2319/70 (2013.01); C12Q 2521/501 (2013.01); C12Y 113/11052 (2013.01); G01N 33/534 (2013.01); G01N 2333/90241 (2013.01);
Abstract
The present application provides stable heterobiligands made up of peptide-based IDO1 ligands and small molecule inhibitors of IDO1 and methods of use of the heterobiligands as detection, imaging, diagnostic, and therapeutic agents. The application further provides methods of manufacturing IDO1 heterobiligands, capture agents, and imaging agents.