The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Mar. 15, 2023
Applicant:

National Technology & Engineering Solutions of Sandia, Llc, Albuquerque, NM (US);

Inventors:

Di Liu, Emeryville, CA (US);

Peter Britton Otoupal, Oakland, CA (US);

HeeJin Hwang, Emeryville, CA (US);

John Michael Gladden, Martinez, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/52 (2006.01); C12N 1/20 (2006.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12P 7/52 (2013.01); C12N 1/205 (2021.05); C12N 9/22 (2013.01); C12N 2310/20 (2017.05);
Abstract

Methods and compositions (e.g., engineered hosts) are disclosed for use in converting biomass to 3-hydropropionic acid. In particular embodiments, the methods include use of an engineeredyeast, such as, the engineeredhaving the RT04_8975 gene deleted from its genome, combined with a lignocellulosic hydrolysate, sourced, for example, from a biomass. A promoter for enhancing transport of 3HP is also incorporated by addition to thegenome, for example, by modified lithium acetate transformation.


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