The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
May. 03, 2024
Institute of Medical Biology, Cams, Kunming, CN;
Longding Liu, Kunming, CN;
Li Yu, Kunming, CN;
Guorun Jiang, Kunming, CN;
Dandan Li, Kunming, CN;
Heng Zhao, Kunming, CN;
Huiwen Zheng, Kunming, CN;
Ying Zhang, Kunming, CN;
Yun Liao, Kunming, CN;
Haijing Shi, Kunming, CN;
Xin Zhao, Kunming, CN;
Heng Li, Kunming, CN;
INSTITUTE OF MEDICAL BIOLOGY, CAMS, Kunming, CN;
Abstract
Provided is a Coxsackievirus A6 (CVA6) strain CVA6-KM-J33 and use thereof, and belongs to the technical field of biomedicine. The present invention provides a CVA6 strain CVA6-KM-J33, which belongs to a CVA6 virus. In the present invention, the strain CVA6-KM-J33 is susceptible to KMB17 cells and can achieve a relatively high titer. The strain has strong virulence, high pathogenicity and lethality to suckling mice, and desirable immunogenicity, and is a highly effective virus strain for CVA6 vaccine development. This strain can be used for immunogenicity evaluation or protective evaluation of CVA6 vaccine to improve the accuracy and reproducibility of vaccine immunogenicity evaluation. This strain can also be used to prepare animal models of Coxsackievirus (CV) infection, and exhibits desirable application prospects.