The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Apr. 11, 2019
Applicant:
Umoja Biopharma, Inc., Seattle, WA (US);
Inventors:
Andrew Scharenberg, Seattle, WA (US);
Laurie Beitz, Seattle, WA (US);
Assignee:
Umoja Biopharma, Inc., Seattle, WA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 9/00 (2006.01); A61K 31/436 (2006.01); A61K 38/13 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); C07K 14/55 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/436 (2013.01); A61K 38/13 (2013.01); A61K 38/177 (2013.01); A61K 38/1774 (2013.01); A61K 38/1793 (2013.01); A61K 39/3955 (2013.01); C07K 14/55 (2013.01); C07K 14/70532 (2013.01); C07K 14/70578 (2013.01); C07K 16/2809 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01); C12N 2740/15032 (2013.01); C12N 2740/15041 (2013.01); C12N 2740/15043 (2013.01); C12N 2740/15052 (2013.01); C12N 2740/16032 (2013.01); C12N 2740/16041 (2013.01); C12N 2740/16052 (2013.01);
Abstract
The disclosure relates generally to nucleic acid vectors and packaging cell lines for in vivo expansion of T-cells. More particularly, the disclosure relates to direct intratumoral injection of a lentiviral vector adapted for transduction and drug-mediated expansion of tumor-infiltrating lymphocytes in vivo.