The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Jun. 01, 2021
Csir, Pretoria, ZA;
University of Cape Town, Cape Town, ZA;
Onderstepoort Biological Products Soc Ltd, Pretoria, ZA;
Albertha René Van Zyl, Wynberg, ZA;
Ann Elizabeth Meyers, Plumstead, ZA;
Daria Anna Rutkowska, Centurion, ZA;
Edward Peter Rybicki, Cape Town, ZA;
Hester Catharina Stark, Irene, ZA;
Martha Magaretha O'Kennedy, Pretoria, ZA;
Nobalanda Betty Mokoena, Montana, ZA;
Abstract
This invention relates to a second generation, plant-produced synthetic Orbivirus candidate vaccine. The vaccine comprises a plant produced chimaeric Orbivirus virus like particle (VLP) comprising at least one structural protein from one Orbivirus serotype and at least one structural protein selected from another serotype of the Orbivirus, wherein both structural capsid proteins are from the same Orbivirus species. In particular the invention relates to a vaccine against an Orbivirus, a method of producing chimaeric Orbivirus virus-like particles (VLPs) for use in a method of prevention and/or treatment of an Orbivirus infection, the use of the chimaeric Orbivirus VLPs in the manufacture of a vaccine for an Orbivirus, and a method of preventing and/or treating an Orbivirus infection.