The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Jan. 11, 2019
Applicants:
Crispr Therapeutics Ag, Zug, CH;
Bayer Healthcare Llc, Whippany, NJ (US);
Inventors:
Alan Richard Brooks, Cambridge, MA (US);
Karen Vo, Cambridge, MA (US);
Assignees:
CRISPR Therapeutics AG, Zung, CH;
BAYER HEALTHCARE LLC, Whippany, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 35/407 (2015.01); C12N 9/22 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 35/407 (2013.01); C12N 9/22 (2013.01); C12N 15/86 (2013.01); C12N 2510/00 (2013.01); C12N 2750/14143 (2013.01); C12N 2830/42 (2013.01); C12N 2830/50 (2013.01);
Abstract
Provided include compositions, methods, and systems for modulating the expression, function, and/or activity of a target gene, for example a blood-clotting protein such as Factor VIII (FVIII), in a cell by genome editing. Also provided include compositions, methods, and systems for treating a subject having or suspected of having a disorder or health condition, e.g., Hemophilia A, employing ex vivo and/or in vivo genome editing.