The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Jun. 17, 2024
Applicant:

Tongji Hospital, Tongji Medical College of Hust, Wuhan, CN;

Inventors:

Congyi Wang, Wuhan, CN;

Shanjie Rong, Wuhan, CN;

Fei Sun, Wuhan, CN;

Chunliang Yang, Wuhan, CN;

Jiahui Luo, Wuhan, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61P 3/10 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61P 3/10 (2018.01); A61K 2039/505 (2013.01); C07K 2317/14 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present disclosure relates to the technical field of chemoimmunology, and in particular to an anti-receptor expressed on lymphoid tissues (RELT) recombinant monoclonal antibody and a preparation method and use thereof. The anti-RELT recombinant monoclonal antibody includes a heavy chain variable region and a light chain variable region, where the amino acid sequence of the heavy chain variable region is set forth in SEQ ID NO: 4; the amino acid sequence of the light chain variable region is set forth in SEQ ID NO: 5; and the anti-RELT recombinant monoclonal antibody has a biological activity of neutralizing a function of RELT. In addition, because the anti-RELT recombinant monoclonal antibody has the biological activity of neutralizing the function of RELT, the anti-RELT recombinant monoclonal antibody can specifically recognize and detect the expression of RELT in different tissues and cells.


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