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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12215147 B1

PDFFull Text
Date of Patent:
Feb. 04, 2025

Filed:

Aug. 23, 2021

Methods of selecting, based on polymorphisms, an inflammatory bowel disease subject for treatment with an anti-tl1a antibody

Applicants:

Prometheus Biosciences, Inc., San Diego, CA (US);

Cedars-sinai Medical Center, Los Angeles, CA (US);

Inventors:

Laurens Kruidenier, San Diego, CA (US);

Mahyar Sabripour, San Diego, CA (US);

Janine Bilsborough, Los Angeles, CA (US);

Dermot P. McGovern, Los Angeles, CA (US);

Dalin Li, Los Angeles, CA (US);

Assignees:

PROMETHEUS BIOSCIENCES, INC., San Diego, CA (US);

CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Robert S Landsman

Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); A61P 1/00 (2006.01); A61P 1/04 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/241 (2013.01); A61P 1/00 (2018.01); A61P 1/04 (2018.01); C07K 16/2875 (2013.01); C12Q 1/6883 (2013.01); A61K 2039/505 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01);
Abstract

Provided are methods, systems, and kits for selecting a patient for treatment with a therapeutic agent based on a presence of a genotype associated with a positive therapeutic response to the therapeutic agent. The therapeutic agent, in some embodiments, is an inhibitor of TL1A activity or expression, such as for example, an anti-TL1A antibody.

Find Patent Forward Citations

Kruidenier, Laurens. (2025). Methods of selecting, based on polymorphisms, an inflammatory bowel disease subject for treatment with an anti-tl1a antibody (U.S. Patent No. 12215147). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12215147

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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