The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Apr. 04, 2023
Applicant:
The Catholic University of Korea Industry-academic Cooperation Foundation, Seoul, KR;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/14 (2006.01); A61K 9/127 (2006.01); A61K 39/00 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 14/735 (2006.01); C07K 14/74 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 14/70535 (2013.01); A61K 39/4611 (2023.05); A61K 39/464453 (2023.05); A61K 39/464491 (2023.05); A61K 39/464838 (2023.05); C07K 14/70532 (2013.01); C07K 14/70539 (2013.01); C07K 14/70596 (2013.01); C07K 14/7151 (2013.01); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); C12N 2501/25 (2013.01); C12N 2501/51 (2013.01); C12N 2501/599 (2013.01);
Abstract
The present invention relates to an exosome for stimulating T cells and the pharmaceutical use thereof. Immune exosomes secreted from artificial antigen-presenting cells which express HLA, CD32, and co-stimulatory molecules CD32, CD80, CD83, and 4-1BBL are used to stimulate naive CD8+ T cells whereby preventive and therapeutic effects on tumors, pathogen infections, or autoimmune diseases can be provided.