The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Mar. 08, 2019
Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Abdelghani Abe Achab, Melrose, MA (US);

Matthew L. Childers, Medfield, MA (US);

Jared N. Cumming, Winchester, MA (US);

Christian Fischer, Natick, MA (US);

Symon Gathiaka, Waltham, MA (US);

Hakan Gunaydin, Somerville, MA (US);

Charles A. Lesburg, Newton, MA (US);

Derun Li, West Roxbury, MA (US);

Min Lu, Brookline, MA (US);

Anandan Palani, Needham, MA (US);

Rachel L. Palte, Melrose, MA (US);

Qinglin Pu, Needham, MA (US);

David L. Sloman, Brookline, MA (US);

Sung-Sau So, Verona, NJ (US);

Chunrui Sun, Westfield, NJ (US);

Hongjun Zhang, Boston, MA (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); C07K 16/2818 (2013.01);
Abstract

Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.


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