The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Dec. 10, 2020
Applicant:

Biocoat, Incorporated, Horsham, PA (US);

Inventors:

William James Work, Perkiomenville, PA (US);

Raymond Joseph Gould, Thorndale, PA (US);

Dhruv Patel, Colmar, PA (US);

Robert W Hergenrother, Huntingdon Valley, PA (US);

Assignee:

Biocoat, Incorporated, Horsham, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 25/10 (2013.01); A61K 31/145 (2006.01); A61K 31/155 (2006.01); A61K 31/165 (2006.01); A61K 31/166 (2006.01); A61K 31/167 (2006.01); A61K 31/437 (2006.01); A61K 31/4409 (2006.01); A61K 31/473 (2006.01); A61K 31/502 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61K 31/52 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/655 (2006.01); A61K 31/7008 (2006.01); A61K 31/7048 (2006.01); A61K 31/7076 (2006.01); A61K 31/708 (2006.01); A61L 29/08 (2006.01); A61L 29/16 (2006.01); B05D 5/00 (2006.01); B05D 7/00 (2006.01);
U.S. Cl.
CPC ...
A61M 25/10 (2013.01); A61K 31/145 (2013.01); A61K 31/155 (2013.01); A61K 31/165 (2013.01); A61K 31/166 (2013.01); A61K 31/167 (2013.01); A61K 31/437 (2013.01); A61K 31/4409 (2013.01); A61K 31/473 (2013.01); A61K 31/502 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/52 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/655 (2013.01); A61K 31/7008 (2013.01); A61K 31/7048 (2013.01); A61K 31/7076 (2013.01); A61K 31/708 (2013.01); A61L 29/085 (2013.01); A61L 29/16 (2013.01); B05D 5/00 (2013.01); B05D 7/542 (2013.01); B05D 7/544 (2013.01); A61L 2300/204 (2013.01); A61L 2300/206 (2013.01); A61L 2300/208 (2013.01); A61L 2300/21 (2013.01); A61L 2300/216 (2013.01); A61L 2300/232 (2013.01); A61L 2300/402 (2013.01); A61L 2300/404 (2013.01); A61L 2300/406 (2013.01); A61L 2300/41 (2013.01); A61L 2300/416 (2013.01); A61L 2300/442 (2013.01); A61L 2420/02 (2013.01); A61L 2420/08 (2013.01); A61M 2025/105 (2013.01); A61M 2207/00 (2013.01);
Abstract

The present invention is an implantable medical device comprising (i) a base coat layer having an inner and outer surface, the inner surface of the base coat layer contacting the implantable medical device; (ii) a top-coat layer of a hydrophilic polymer chemically crosslinked and covalently bonded to the outer surface of the base coat layer, the hydrophilic polymer comprising an anionic polyelectrolyte; and (iii) an amount of a hydrophilic cationic drug agent added to the top-coat layer sufficient to provide an effective dosage of the drug agent for delivery to a patient, whereby the hydrophilic cationic drug agent is initially adsorbed into the anionic polyelectrolyte of the top-coat layer and the hydrophilic cationic drug agent having a release rate after the medical device is implanted within a patient's body.


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