The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Dec. 20, 2018
Applicant:

Sexton Biotechnologies, Inc., Indianapolis, IN (US);

Inventors:

Steven Charlebois, West Lafayette, IN (US);

Sreedhar Thirumala, Zionsville, IN (US);

Assignee:

SEXTON BIOTECHNOLOGIES, INC., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 2/00 (2006.01); A61K 35/19 (2015.01); A61K 35/28 (2015.01); A61P 37/00 (2006.01); C12N 5/0775 (2010.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
A61L 2/007 (2013.01); A61K 35/19 (2013.01); A61K 35/28 (2013.01); A61P 37/00 (2018.01); C12N 5/0644 (2013.01); C12N 5/0662 (2013.01); A61L 2202/22 (2013.01); C12N 2500/84 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/135 (2013.01); C12N 2501/15 (2013.01);
Abstract

Disclosed are methods for treating platelet compositions (e.g. platelet concentrates and/or platelet lysates) with electron beam radiation, where the compositions are in a frozen state during irradiation with the e-beam radiation. The methods can be conducted using e-beam radiation at doses effective to reduce the pathogen content of the compositions while retaining highly beneficial bioactivities of the compositions. Also disclosed are compositions preparable by the methods, and methods and compositions involving the use of the e-beam treated materials.


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