The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Feb. 17, 2020
Applicants:

Northwestern University, Evanston, IL (US);

The University of North Carolina AT Chapel Hill, Durham, NC (US);

Inventors:

Samuel I. Stupp, Chicago, IL (US);

Melina R. Kibbe, Chapel Hill, NC (US);

Mark R. Karver, Chicago, IL (US);

Erica B. Peters, Durham, NC (US);

Miranda So, Highland Park, NJ (US);

Neel Anand Mansukhani, Chicago, IL (US);

Mazen Albaghdadi, Brookline, MA (US);

Nick D. Tsihlis, Durham, NC (US);

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 31/195 (2006.01); A61K 38/17 (2006.01); A61K 47/65 (2017.01); A61P 9/10 (2006.01); C07K 14/775 (2006.01);
U.S. Cl.
CPC ...
A61K 9/127 (2013.01); A61K 31/195 (2013.01); A61K 38/1709 (2013.01); A61K 47/65 (2017.08); A61P 9/10 (2018.01); C07K 14/775 (2013.01);
Abstract

Provided herein are peptide amphiphiles (PAs). In some embodiments, provided herein are targeting PAs comprising a PA backbone and a targeting moiety. In some embodiments, provided herein are therapeutic PAs comprising a PA backbone and a therapeutic agent. In some embodiments, the peptide amphiphiles are co-assembled into nanofibers. In some embodiments, the nanofibers may be used for the treatment of atherosclerosis or related disease.


Find Patent Forward Citations

Loading…