The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Aug. 03, 2018
Applicants:

The Hospital for Sick Children, Toronto, CA;

The Governing Council of the University of Toronto, Toronto, CA;

Inventors:

Jean-Philippe Julien, Toronto, CA;

Taylor Sicard, Toronto, CA;

Anthony Semesi, Toronto, CA;

Bebhinn Treanor, Toronto, CA;

Tiantian Zhao, Toronto, CA;

Edurne Rujas Diez, Toronto, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 39/015 (2006.01); A61K 47/68 (2017.01); C07K 14/445 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/6929 (2017.08); A61K 39/015 (2013.01); A61K 47/68 (2017.08); C07K 14/445 (2013.01); B82Y 5/00 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2319/735 (2013.01);
Abstract

A fusion protein comprises a nanocage monomer; and an antibody or fragment thereof linked to the nanocage monomer, the antibody or fragment thereof comprising a first member of a binding pair; wherein a plurality of the fusion proteins self-assemble to form a nanocage in which a plurality of the antibodies or fragments thereof decorate the exterior surface of the nanocage, whereby the first member of the binding pair is exposed for interacting with a second member of a binding pair.


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