The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Jul. 22, 2015
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventor:
Andrea Facciabene, Philadelphia, PA (US);
Assignee:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, Philadelphia, PA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 35/15 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 39/4622 (2023.05); A61K 35/15 (2013.01); A61K 39/4615 (2023.05); A61K 39/464499 (2023.05); A61K 2035/122 (2013.01);
Abstract
The invention provides compositions and methods for cancer immunotherapy. Specifically, the invention provides an antigen-presenting cell, for example, a dendritic cell that comprises a tumor mitochondrial molecule or a tumor mitochondrial molecule derived from tumor mitochondrial protein lysate or a specific mitochondria derived protein of mitochondrial protein lysate as antigen source.