The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2025

Filed:

Feb. 01, 2019
Applicants:

University of Maryland, Baltimore, Baltimore, MD (US);

Regenerative Research Foundation, Rensselaer, NY (US);

Steven Lance Bernstein, Chevy Chase, MD (US);

Candace L. Kerr, Westminster, MD (US);

Sally Temple Stern, Slingerlands, NY (US);

Inventors:

Steven Lance Bernstein, Chevy Chase, MD (US);

Candace L. Kerr, Westminster, MD (US);

Sally Temple Stern, Slingerlands, NY (US);

Assignees:

UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);

REGENERATIVE RESEARCH FOUNDATION, Rensselaer, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/30 (2015.01); A61K 38/18 (2006.01); A61P 27/06 (2006.01);
U.S. Cl.
CPC ...
A61K 35/30 (2013.01); A61K 38/18 (2013.01); A61K 38/1825 (2013.01); A61K 38/1841 (2013.01); A61K 38/185 (2013.01); A61K 38/1866 (2013.01); A61P 27/06 (2018.01);
Abstract

Optic nerve lamina region neural progenitor cells (ONLR-NPCs) are provided. Such cells secrete growth factors and survival factors that can be used in the treatment of optic nerve diseases, such as glaucoma. Also provided are methods of treating or preventing optic nerve diseases, such as glaucoma, using one or more factors secreted by ONLR-NPCs, combinations of factors secreted by ONLR-NPCs, or culture media conditioned by ONLR-NPCs.


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