The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Oct. 18, 2022
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Richard Bruce Silverman, Evanston, IL (US);
Pathum Manjula Weerawarna, Evanston, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); A61K 45/06 (2006.01); A61P 31/04 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); C07D 401/12 (2013.01);
Abstract
Disclosed are substituted aminoquinoline and aminopyridine compounds and their use as bacterial nitric oxide synthase (bNOS) inhibitors. Also disclosed are pharmaceutical compositions comprising the compounds, and methods of using the compounds and pharmaceutical compositions for treating a subject having or at risk for developing a disease or disorder that is associated with bNOS activity.