The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2025

Filed:

May. 30, 2019
Applicant:

Arex Life Sciences, Llc, Watertown, MA (US);

Inventor:

Barb A. Cohen, Watertown, MA (US);

Assignee:

AREX LIFE SCIENCES, LLC, Watertown, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); A01N 1/02 (2006.01); A61B 17/43 (2006.01); A61D 19/02 (2006.01); C12N 5/076 (2010.01);
U.S. Cl.
CPC ...
G01N 33/689 (2013.01); A01N 1/0284 (2013.01); A61B 17/43 (2013.01); A61D 19/02 (2013.01); C12N 5/061 (2013.01); A61B 2503/40 (2013.01); C12N 2501/01 (2013.01); C12N 2501/999 (2013.01);
Abstract

In accord with the present invention, the fertility quality of an ejaculate can be determined by assaying sperm, in aliquots of the ejaculate or of an ejaculate produced previously by the same male, at intervals over a period of time. Fertility quality is determined by the number of times the level of expression of a marker on the sperm goes through a maximum level of expression during the period of time and if desired by sperm state and fertilization procedure used. The marker should be capable of correlation with the level of Fc receptor (FcR) expression on the sperm. The fertility quality of the ejaculate is related to the number of times a maximum level of expression is reached.


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