The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2025
Filed:
Jun. 26, 2019
Applicant:
Altius Institute for Biomedical Sciences, Seattle, WA (US);
Inventors:
John A. Stamatoyannopoulos, Seattle, WA (US);
Fyodor Urnov, Seattle, WA (US);
Jocelynn Pearl, Seattle, WA (US);
Sean Thomas, Seattle, WA (US);
Assignee:
Altius Institute for Biomedical Sciences, Seattle, WA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C07K 19/00 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C07K 19/00 (2013.01); C12N 15/52 (2013.01); C07K 2319/81 (2013.01);
Abstract
DNA cleaving enzymes are disclosed. The DNA cleaving enzymes are fused to a heterologous DNA binding domain that is designed to bind to a target nucleic acid sequence. Nucleic acids and expression cassettes encoding the DNA cleaving enzymes are also provided. Methods for genome editing using the DNA cleaving enzymes, fusion proteins, and compositions thereof are disclosed herein.