The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2025

Filed:

Nov. 26, 2019
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Alec Nathanson Flyer, Boston, MA (US);

Andrei Alexandrovich Golosov, Cambridge, MA (US);

Philipp Grosche, Inzlingen, DE;

Ian Lewis, Riehen, CH;

Eugene Yuejin Liu, Lexington, MA (US);

Andreas Marzinzik, Weil am Rhein, DE;

Lauren Gilchrist Monovich, Belmont, MA (US);

Johannes Ottl, Lörrach, DE;

Tajesh Jayprakash Patel, Westford, MA (US);

Patrick Crawford Reid, Tokyo, JP;

Mohindra Seepersaud, Acton, MA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/64 (2006.01); A61K 38/12 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/64 (2013.01); A61K 38/12 (2013.01); A61K 45/06 (2013.01); A61K 38/00 (2013.01);
Abstract

The disclosure relates to inhibitors of PCSK9 useful in the treatment of lipid metabolism, and other diseases in which PCSK9 plays a role, having the Formula (I):


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