The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2025
Filed:
May. 21, 2019
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Steven McKerrall, South San Francisco, CA (US);
Ramsay Beveridge, Quebec, CA;
Kwong Wah Lai, Shanghai, CN;
Philippe Bergeron, South San Francisco, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 9/00 (2006.01); A61P 17/04 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 9/0014 (2013.01); A61P 17/04 (2018.01); A61P 29/00 (2018.01);
Abstract
The invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein the variables Y-Y, X, Z, Z, Z, R-R, and Rhave the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions. The compounds have sodium channel blocking activity that are useful for treating sodium channel-mediated diseases, in particular for treating pain.