The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2025
Filed:
Aug. 15, 2018
Bgi Shenzhen, Shenzhen, CN;
Zhao-Hui Wang, Shenzhen, CN;
Hui Wang, Shenzhen, CN;
Cheng-Mei Xing, Shenzhen, CN;
Han-Dong Li, Shenzhen, CN;
Wen-Wei Zhang, Shenzhen, CN;
Jay Willis Shafto, Shenzhen, CN;
Mei-Hua Gong, Shenzhen, CN;
Jin Yang, Shenzhen, CN;
Yin-Ling Luo, Shenzhen, CN;
Zhen-Hua Zhang, Shenzhen, CN;
Yuan Li, Shenzhen, CN;
Xue-Qin Jiang, Shenzhen, CN;
BGI SHENZHEN, Shenzhen, CN;
Abstract
A gene chip includes a chip carrier, a plurality of DNA nanoballs assembled on the chip carrier, and a polymer film formed on the chip carrier and wrapping the DNA nanoballs. The polymer film includes at least one of a film of a positively charged polymer, a film of a positively charged polymer which is modified, a film of a zwitterionic polymer, and a composite polymer film. The composite polymer film is formed by a layer-by-layer self-assembly process of a positively charged polymer and a negatively charged polymer. The gene chip has good sequencing quality and different functions can be achieved by coating with different polymers, such as the chip surface rapidly drying out and surface non-specific adsorption. A method of preparing a gene chip is further disclosed.