The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2025
Filed:
Feb. 18, 2019
Applicant:
Boise State University, Boise, ID (US);
Inventor:
Daniel Fologea, Boise, ID (US);
Assignee:
BOISE STATE UNIVERSITY, Boise, ID (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61K 9/127 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61N 5/06 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0038 (2013.01); A61K 9/1272 (2013.01); A61K 9/1273 (2013.01); A61K 38/164 (2013.01); A61K 38/1767 (2013.01); A61N 5/0601 (2013.01); A61N 2005/0661 (2013.01); A61N 2005/1098 (2013.01);
Abstract
The present disclosure is directed to radiation triggered liposomes and their use in delivery and release of pharmaceutical drugs upon exposure to ionizing radiation. In one embodiment liposomes are provided that comprise cholesterol and sphingolipids modified to comprise reactive groups that are activated by ionizing radiation to form crosslinks with other lipids of the liposome causing the release of the liposomal contents.