The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2025

Filed:

Feb. 08, 2023
Applicant:

Juno Therapeutics, Inc., Seattle, WA (US);

Inventors:

Chris Ramsborg, Seattle, WA (US);

Mark L. Bonyhadi, Sammamish, WA (US);

Calvin Chan, Seattle, WA (US);

Pascal Beauchesne, Seattle, WA (US);

Assignee:

Juno Therapeutics, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 35/12 (2015.01); C12N 5/0783 (2010.01); C12N 5/10 (2006.01); C12M 1/00 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
A61K 39/4631 (2023.05); A61K 39/4611 (2023.05); A61K 39/4644 (2023.05); A61K 39/464412 (2023.05); C12N 5/0636 (2013.01); C12N 5/10 (2013.01); A61K 2035/124 (2013.01); C12M 47/04 (2013.01); G01N 33/56972 (2013.01); G01N 2333/70514 (2013.01); G01N 2333/70517 (2013.01);
Abstract

The present disclosure relates in some aspects to methods, cells, and compositions for preparing cells and compositions for genetic engineering and cell therapy. Provided in some embodiments are streamlined cell preparation methods, e.g., for isolation, processing, incubation, and genetic engineering of cells and populations of cells. Also provided are cells and compositions produced by the methods and methods of their use. The cells can include immune cells, such as T cells, and generally include a plurality of isolated T cell populations or types. In some aspects, the methods are capable of preparing of a plurality of different cell populations for adoptive therapy using fewer steps and/or resources and/or reduced handling compared with other methods.


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