The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2025

Filed:

Mar. 20, 2023
Applicant:

Biontech SE, Mainz, DE;

Inventors:

Alexander Muik, Seeheim-Jugenheim, DE;

Kena Anne Swanson, Pearl River, NY (US);

Qi Yang, Orangeburg, NY (US);

Hui Cai, Ridgewood, NJ (US);

Ugur Sahin, Mainz, DE;

Kayvon Modjarrad, Chevy Chase, MD (US);

Assignee:

BioNTech SE, Mainz, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2006.01); A61K 9/127 (2006.01); A61K 39/145 (2006.01); A61K 45/06 (2006.01); A61K 47/26 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/215 (2013.01); A61K 9/1272 (2013.01); A61K 39/145 (2013.01); A61K 45/06 (2013.01); A61K 47/26 (2013.01); C12N 15/86 (2013.01); A61K 2039/53 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55555 (2013.01); C12N 2310/335 (2013.01); C12N 2760/16022 (2013.01); C12N 2760/16034 (2013.01); C12N 2770/20022 (2013.01); C12N 2770/20034 (2013.01); C12N 2770/20043 (2013.01); C12N 2770/20071 (2013.01);
Abstract

This disclosure relates to the field of RNA to prevent or treat coronavirus infection. In particular, the present disclosure relates to methods and agents for vaccination against coronavirus infection and inducing effective coronavirus antigen-specific immune responses such as antibody and/or T cell responses. Specifically, in one embodiment, the present disclosure relates to methods comprising administering to a subject RNA encoding a peptide or protein comprising an epitope of SARS-CoV-2 spike protein (S protein) for inducing an immune response against coronavirus S protein, in particular S protein of SARS-CoV-2, in the subject, i.e., vaccine RNA encoding vaccine antigen.


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