The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2025
Filed:
Jun. 23, 2022
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Vesselina Cooke, Cambridge, MA (US);
Michael Scott Visser, Cambridge, MA (US);
Andrew Wylie, Newton, MA (US);
Padmaja Yerramilli-Rao, Cambridge, MA (US);
Xu Zhu, Cambridge, MA (US);
Assignee:
NOVARTIS AG, Basel, CH;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/497 (2013.01); A61K 9/0053 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract
The present disclosure relates to use of a protein kinase C (PKC) inhibitor in the treatment or prevention of proliferative diseases. The disclosure also relates to corresponding pharmaceutical formulations, uses, methods, combinations, and related disclosure embodiments. The disclosure further relates to use of a pharmaceutical combination comprising a PKC inhibitor and another therapeutic agent, such as an MDM2 inhibitor, in the treatment or prevention of a proliferative disease.