The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2025

Filed:

Apr. 12, 2021
Applicant:

George Mason Research Foundation, Inc., Fairfax, VA (US);

Inventors:

Fatah Kashanchi, Potomac, MD (US);

Catherine DeMarino, Annandale, VA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/352 (2006.01); A61K 31/05 (2006.01); A61K 45/06 (2006.01); A61P 31/18 (2006.01);
U.S. Cl.
CPC ...
A61K 31/352 (2013.01); A61K 31/05 (2013.01); A61K 45/06 (2013.01); A61P 31/18 (2018.01);
Abstract

This disclosure relates to methods and compositions for inhibiting release of extracellular vesicles from a cell infected by a virus. One aspect of the disclosure relates to methods for treating viral diseases, reducing damage to a neuron from the central neural system ('CNS') and/or treating neuroinflammation in a subject. In another aspect, provided herein are methods for inhibiting transcription of a viral RNA and/or release of extracellular vesicles from a cell infected by a virus.


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