The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Mar. 01, 2019
Genzyme Corporation, Cambridge, MA (US);
Dhanuka Pulasthi Wasalathanthri, Fiskdale, MA (US);
Jagdish C. Tewari, Bridgewater, NJ (US);
Xuezhen Kang, Bridgewater, NJ (US);
Marina Hincapie, Bridgewater, NJ (US);
Shawn L. Barrett, Bridgewater, NJ (US);
Julie Susanne Pollock, Bridgewater, NJ (US);
Genzyme Corporation, Cambridge, MA (US);
Abstract
The disclosure features methods that include obtaining a vibrational spectrum of a solution in a biological manufacturing system, analyzing the vibrational spectrum using a first chemometrics model to determine a value of a first quality attribute associated with the solution, analyzing the vibrational spectrum using a second chemometrics model to determine a value of a second quality attribute associated with the solution, and adjusting at least one parameter of a purification unit of the biological manufacturing system based on at least one of the values of the first and second quality attributes.