The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

Jul. 03, 2020
Applicant:

Bostongene Corporation, Waltham, MA (US);

Inventors:

Ekaterina Nuzhdina, Moscow, RU;

Alexander Bagaev, Moscow, RU;

Maksim Chelushkin, Moscow, RU;

Yaroslav Lozinsky, Moscow, RU;

Natalia Miheecheva, Moscow, RU;

Aleksandr Zaitsev, Drozhzhino, RU;

Assignee:

BostonGene Corporation, Waltham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 30/10 (2019.01); C12Q 1/6806 (2018.01); C12Q 1/6869 (2018.01); G16B 20/00 (2019.01); G16B 20/20 (2019.01); G16B 25/10 (2019.01); G16B 35/10 (2019.01); G16H 50/30 (2018.01);
U.S. Cl.
CPC ...
G16B 30/10 (2019.02); C12Q 1/6806 (2013.01); C12Q 1/6869 (2013.01); G16B 20/00 (2019.02); G16B 20/20 (2019.02); G16B 25/10 (2019.02); G16B 35/10 (2019.02); G16H 50/30 (2018.01);
Abstract

Described herein are various methods of collecting and processing of tumor and/or healthy tissue samples to extract nucleic acid and perform nucleic acid sequencing. Also described herein are various methods of processing nucleic acid sequencing data to remove bias from the nucleic acid sequencing data. Also described herein are various methods of evaluating the quality of nucleic acid sequence information. The identity and/or integrity of nucleic acid sequence data is evaluated prior to using the sequence information for subsequent analysis (for example for diagnostic, prognostic, or clinical purposes). The methods enable a subject, doctor, or user to characterize or classify various types of cancer precisely, and thereby determine a therapy or combination of therapies that may be effective to treat a cancer in a subject based on the precise characterization.


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