The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

Feb. 22, 2021
Applicants:

The University of Vermont and State Agricultural College, Burlington, VT (US);

Universiteit Maastricht, Maastricht, NL;

Inventors:

Yvonne M. Janssen-Heininger, Charlotte, VT (US);

Niki Reynaert, Maasmechelen, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/58 (2006.01); G01N 33/573 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/58 (2013.01); G01N 33/573 (2013.01); G01N 33/6815 (2013.01); G01N 33/6842 (2013.01); G01N 33/6893 (2013.01); G01N 2333/902 (2013.01); G01N 2800/122 (2013.01); G01N 2800/24 (2013.01);
Abstract

The present invention, in some aspects, relates to systems and methods for determining oxidized proteins, including glutathionylated proteins such as S-glutathionylated proteins. The systems and methods of the invention can be used in vitro (e.g., in cell or tissue culture) or in vivo, for example, to diagnose a person having an oxidative stress condition. For instance, in some cases, the invention can be used to spatially determine the location and/or concentration of oxidized proteins within cells and/or tissues (e.g., through visual detection).


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