The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

Aug. 15, 2019
Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

M. Cristine Charlesworth, Rochester, MN (US);

Sanjeev Sethi, Rochester, MN (US);

Fernando C. Fervenza, Rochester, MN (US);

Benjamin J. Madden, Stewartville, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/564 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); G01N 2333/705 (2013.01); G01N 2333/91102 (2013.01); G01N 2800/347 (2013.01);
Abstract

This document provides methods and materials involved in identifying and treating mammals (e.g., humans) having membranous nephropathy. For example, methods and materials for detecting the presence of autoantibodies specific for an EXT1 and/or EXT2 polypeptide as well as methods and materials for detecting the presence of kidney tissue having an elevated level of an EXT1 and/or EXT2 polypeptide are provided. In addition, methods and materials for treating membranous nephropathy by administering an immunosuppressant are provided.


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