The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

Mar. 19, 2019
Applicants:

Crispr Therapeutics Ag, Zug, CH;

Bayer Healthcare Llc, Whippany, NJ (US);

Inventors:

Andre Cohnen, Titz-Hasselsweiler, DE;

Moritz Schmidt, Cologne, DE;

Wayne Coco, Pulheim, DE;

Michael Biag Gamalinda, Leverkusen, DE;

Ashish Gupta, Leverkusen, DE;

Christian Pitzler, Leverkusen, DE;

Florian Richter, Leverkusen, DE;

Jan Tebbe, Leverkusen, DE;

Christopher Cheng, Cambridge, MA (US);

Ryo Takeuchi, Cambridge, MA (US);

Caroline W. Reiss, Cambridge, MA (US);

Assignees:

CRISPR THERAPEUTICS AG, Zug, CH;

BAYER HEALTHCARE LLC, Whippany, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/113 (2013.01); C12N 15/907 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract

Aspects of this invention, inter alia, relate to novel systems for targeting, editing or manipulating DNA in a cell, using novel synthetic RNA-guided nucleases (sRGNs). The sRGNs are derived from wildtype or parental small type II CRISPR Cas9 endonucleases.


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