The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Oct. 19, 2020
Applicant:
Homology Medicines, Inc., Bedford, MA (US);
Inventors:
Albert Barnes Seymour, Westborough, MA (US);
Seemin Seher Ahmed, Worcester, MA (US);
Jason Boke Wright, Concord, MA (US);
Serena Nicole Dollive, Waltham, MA (US);
James Anthony McSwiggen, Arlington, MA (US);
Jaime Michelle Prout, Hudson, NH (US);
Danielle Lauren Sookiasian, Quincy, MA (US);
Assignee:
Homology Medicines, Inc., Bedford, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 35/761 (2015.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); A61K 35/761 (2013.01); C12N 7/00 (2013.01); C12N 2710/10033 (2013.01); C12N 2710/10052 (2013.01); C12N 2750/14121 (2013.01); C12N 2750/14143 (2013.01);
Abstract
Provided herein are adeno-associated virus (AAV) compositions that can restore phenylalanine hydroxylase (PAH) gene function in cell. Also provided are methods of use of the AAV compositions, and packaging systems for making the AAV compositions.