The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Dec. 21, 2020
Applicant:
Case Western Reserve University, Cleveland, OH (US);
Inventor:
Nicole F. Steinmetz, San Diego, CA (US);
Assignee:
CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 45/06 (2006.01); A61K 47/62 (2017.01); A61K 47/69 (2017.01); C12N 7/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 45/06 (2013.01); A61K 47/62 (2017.08); A61K 47/6929 (2017.08); C12N 7/00 (2013.01); C12N 2310/14 (2013.01); C12N 2770/14023 (2013.01);
Abstract
A nanoparticle includes an icosahedral-shaped plant virus particle; an RNAi construct; and one or more endolysosomal release agents, wherein the RNAi construct is noncovalently loaded within the icosahedral-shaped plant virus particle.