The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Jun. 07, 2019
Applicant:
Argenx Bv, Ghent, BE;
Inventors:
Hans De Haard, Oudelande, NL;
Peter Ulrichts, Destelbergen, BE;
Thierry Cousin, Bordeaux, FR;
Nicolas Leupin, Zurich, CH;
Torsten Dreier, Sint Martens Latem, BE;
Tonke Van Bragt, Boxtel, NL;
Assignee:
argenx BV, Ghent, BE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/47 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/283 (2013.01); C07K 14/4703 (2013.01); A61K 45/06 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01);
Abstract
A method is disclosed for the treatment of human subjects diagnosed with immune thrombocytopenia (ITP). The method comprises administering to a human subject a human neonatal Fc receptor (hFcRn) antagonist, optionally in combination with standard-of-care ITP treatment. In certain embodiments, the hFcRn antagonist is efgartigimod (ARGX-113). Standard-of-care ITP treatment may comprise administration of corticosteroids, immunosuppressants, and/or thrombopoietin receptor (TPO-R) agonists.