The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Mar. 30, 2020
Applicant:
Statens Serum Institut, Copenhagen S, DK;
Inventors:
Susheel Kumar Singh, Vanlose, DK;
Michael Theisen, Holte, DK;
Assignee:
STATENS SERUM INSTITUT, COPENHAGEN S, DK;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/002 (2006.01); A61P 33/06 (2006.01); A61P 37/04 (2006.01); C07K 1/10 (2006.01); C07K 14/445 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/445 (2013.01); A61P 33/06 (2018.01); A61P 37/04 (2018.01); C07K 1/10 (2013.01); A61K 39/00 (2013.01); A61K 2039/5258 (2013.01);
Abstract
The present invention relates to a method for recombinant production of a fusion protein comprising multiple malaria antigens for inducing immune responses comprising a combination of antibodies. In particular, the fusion proteins of the present invention comprise fragments of both Pfs230 and Pfs48/45 to lower the required threshold of functional antibodies and to reduce the risk of escape mutations. Thus, the fusion proteins of the present invention are suitable for use in a multivalent malaria vaccine.