The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

Jun. 25, 2019
Applicant:

Peter Maccallum Cancer Institute, Melbourne, AU;

Inventors:

Paul Beavis, Reservoir, AU;

Philip Darcy, Yallambie, AU;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07K 14/52 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 16/32 (2006.01); C12N 5/0783 (2010.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 39/4611 (2023.05); A61K 39/4631 (2023.05); A61K 39/4644 (2023.05); A61K 39/464406 (2023.05); A61K 39/464416 (2023.05); A61P 35/00 (2018.01); C07K 14/52 (2013.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 16/32 (2013.01); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); C12N 15/85 (2013.01); A61K 2239/38 (2023.05); A61K 2239/49 (2023.05); A61K 2239/50 (2023.05); C07K 2319/02 (2013.01);
Abstract

The present invention generally relates to T cells that are modified to enhance the efficiency of adoptive cellular therapy by modulating dendritic cell activity, a composition comprising modified T cells, vectors and methods for the treatment of cancer comprising administering modified T cells. In particular, the present invention provides modified T cells for use in adoptive cellular therapies for the treatment of solid tumours.


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