The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

May. 17, 2022
Applicants:

Abivax, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Institut Curie, Paris, FR;

Universite DE Montpellier, Montpellier, FR;

Inventors:

Didier Scherrer, Castelnau le Lez, FR;

Jamal Tazi, Clapiers, FR;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/497 (2006.01); A61K 31/5377 (2006.01); C07D 401/12 (2006.01); C12Q 1/6883 (2018.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07D 215/38 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/497 (2013.01); A61K 31/5377 (2013.01); C07D 401/12 (2013.01); C12Q 1/6883 (2013.01); G01N 33/5023 (2013.01); G01N 33/5055 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract

In vitro or ex vivo methods for screening a quinoline derivative, or anyone of its pharmaceutically acceptable salt, presumed effective in treating and/or preventing an inflammatory disease, the method including: providing an eukaryotic cell, bringing into contact said cell with a quinoline derivative, measuring an expression of miR-124 in the cell, and selecting the candidate presumed effective in treating and/or preventing an inflammatory disease when the level of expression of miR-124 measured is increased relatively to a reference value.


Find Patent Forward Citations

Loading…