The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Sep. 19, 2023
Applicant:
Alonbio Ltd., Nes Ziona, IL;
Inventors:
Assignee:
AlonBio Ltd., Ness Ziona, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/22 (2006.01); A61K 45/06 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
C07D 215/22 (2013.01); A61P 35/04 (2018.01); A61K 45/06 (2013.01);
Abstract
Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B, D, E, G and R-Rare as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.