The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

May. 22, 2020
Applicant:

Know Bio, Llc, Durham, NC (US);

Inventors:

Nicholas William Medendorp, Jr., Durham, NC (US);

Katelyn Reighard Crizer, Durham, NC (US);

Assignee:

KNOW Bio, LLC, Morrisville, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/06 (2006.01); A61K 35/16 (2015.01); A61K 38/18 (2006.01); A61M 1/02 (2006.01);
U.S. Cl.
CPC ...
A61M 1/0259 (2013.01); A61K 35/16 (2013.01); A61K 38/1858 (2013.01); A61M 2202/0415 (2013.01); A61M 2202/0445 (2013.01);
Abstract

Embodiments provide methods and apparatus for fabricating blood products, such as platelet-rich plasma, containing elevated concentrations of growth factors such as platelet derived growth factor. The platelet-rich plasma can be autologous, and the concentration of growth factors (e.g., platelet derived growth factor) is elevated relative to other samples isolated from the same subject. The platelet-rich plasma can be used to promote tissue regeneration, including wound healing, joint repair, hair growth, and the like. The compositions can be combined with stem cells and used to treat disorders otherwise treated with stem cells. The growth factors present in the samples can direct the differentiation of the stem cells.


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