The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Aug. 20, 2021
Applicant:
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Inventors:
Matthew Louis Hirsch, Chapel Hill, NC (US);
Richard Jude Samulski, Chapel Hill, NC (US);
Assignee:
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 9/00 (2006.01); A61K 35/76 (2015.01); A61P 27/00 (2006.01); C07K 14/00 (2006.01); C12N 9/24 (2006.01); C12N 9/26 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 48/00 (2013.01); A61K 9/0019 (2013.01); A61K 9/0048 (2013.01); A61K 35/76 (2013.01); A61P 27/00 (2018.01); C07K 14/00 (2013.01); C12N 9/2402 (2013.01); C12N 9/2411 (2013.01); C12N 15/86 (2013.01); C12Y 302/01076 (2013.01); C12N 2710/10044 (2013.01); C12N 2750/14141 (2013.01); C12N 2750/14143 (2013.01); C12N 2800/22 (2013.01);
Abstract
This invention relates to viral vectors for delivery of alpha-L-iduronidase to the cornea of a subject and methods of using the same for treatment and prevention of corneal clouding and blindness in a subject due to mucopolysaccharidosis I.