The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

Oct. 17, 2018
Applicant:

City of Hope, Duarte, CA (US);

Inventors:

Saswati Chatterjee, Altadena, CA (US);

Kamehameha K. Wong, Jr., Altadena, CA (US);

Marwa BenHajSalah, Duarte, CA (US);

Laura Jane Smith, Westford, MA (US);

Albert Barnes Seymour, Westborough, MA (US);

Jason Boke Wright, Concord, MA (US);

James Anthony McSwiggen, Arlington, MA (US);

Serena Nicole Dollive, Waltham, MA (US);

Thia Baboval St. Martin, Lunenburg, MA (US);

Jaime Michelle Prout, Hudson, NH (US);

Assignee:

CITY OF HOPE, Duarte, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/761 (2015.01); A61K 48/00 (2006.01); C07K 14/075 (2006.01); C07K 14/805 (2006.01); C12N 15/62 (2006.01); C12N 15/86 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); A61K 48/0016 (2013.01); A61K 48/005 (2013.01); A61K 48/0058 (2013.01); C07K 14/075 (2013.01); C07K 14/805 (2013.01); C12N 15/62 (2013.01); C12N 15/86 (2013.01); C12N 15/907 (2013.01); A01K 2207/12 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0381 (2013.01);
Abstract

Provided herein are adeno-associated virus (AAV) compositions for correcting a mutation in a beta globin gene (HBB) gene and methods of using the same to correct an HBB gene mutation in a cell. Also provided are packaging systems for making the adeno-associated virus compositions.


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