The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Dec. 23, 2021
Sage Therapeutics, Inc., Cambridge, MA (US);
Gabriel Martinez Botella, Wayland, MA (US);
Boyd L. Harrison, Princeton Junction, NJ (US);
Albert Jean Robichaud, Boston, MA (US);
Francesco G. Salituro, Marlborough, MA (US);
Richard Thomas Beresis, Shanghai, CN;
Sage Therapeutics, Inc., Cambridge, MA (US);
Abstract
Provided herein are 19-nor C3,3-disubstituted C21-pyrazolyl steroids of Formula (I): and pharmaceutically acceptable salts thereof; wherein, R, R, R, R, R, R, R, R, and Rare as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.