The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

Dec. 26, 2019
Applicant:

Alar Pharmaceuticals Inc., Taichung, TW;

Inventors:

Tong-Ho Lin, Taichung, TW;

Yung-Shun Wen, Taichung, TW;

Ying-Ting Liu, Taichung, TW;

Zhi-Rong Wu, Taichung, TW;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); A61K 9/00 (2006.01); A61K 47/32 (2006.01); A61P 25/30 (2006.01); A61P 25/36 (2006.01);
U.S. Cl.
CPC ...
A61K 31/485 (2013.01); A61K 9/0019 (2013.01); A61K 47/32 (2013.01); A61P 25/30 (2018.01); A61P 25/36 (2018.01);
Abstract

Provided is an injectable sustained release pharmaceutical formulation, including 3-acyl-naltrexone or a pharmaceutically acceptable salt thereof, a biocompatible organic solvent, and optionally a biocompatible polymeric material. Also provided is a method for treating opioid use disorder or alcoholism, including administering the injectable sustained release pharmaceutical formulation to a subject in need thereof. The pharmaceutical formulation provides a sustained release profile after one single injection, and the plasma levels of naltrexone in minipigs could provide a sustained release for 2 months.


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