The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2025

Filed:

Sep. 19, 2022
Applicants:

Technion Research & Development Foundation Limited, Haifa, IL;

Health Corporation—rambam, Haifa, IL;

Inventors:

Asya Rolls, Haifa, IL;

Tamar Ben Shannan, Haifa, IL;

Hilla Azulay-Debbie, Haifa, IL;

Fahed Hakim, Nazareth, IL;

Maya Schiller, Haifa, IL;

Shai Shen-Orr, Karkur, IL;

Elina Starosvetsky, Yokneam Ilit, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61N 2/00 (2006.01); A61K 31/404 (2006.01); A61K 31/4045 (2006.01); A61K 31/428 (2006.01); A61K 31/473 (2006.01); A61K 31/48 (2006.01); A61K 31/506 (2006.01); A61N 2/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/48 (2013.01); A61K 31/404 (2013.01); A61K 31/4045 (2013.01); A61K 31/428 (2013.01); A61K 31/473 (2013.01); A61K 31/506 (2013.01); A61N 2/006 (2013.01); A61N 2/02 (2013.01);
Abstract

A method for modulating an immune response by activating or inhibiting dopaminergic neurons in the Ventral Tegmental Area (VTA) is provided. Modulation is achieved by modulating the activity, the abundance or both of: a natural killer cell, a CD8 T-cell, a CD4 T-cell, a B-cell, a dendritic cell, a macrophage, a granulocyte, or their combination.


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